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Outside the Lab Training and education, Microbiology and immunology, Infectious disease

Why Didn’t They Teach This in Med School?

How would you rate your understanding of epidemiologic terms? 

Reading about COVID-19, you may have encountered the four parameters mentioned in this question. Which one indicates the risk unit defined as one-in-a-million chance of death?

A. Micromort 
B. Microprobability  
C. R0
D. Rt

Read on to see the answer!

Answer: A. Micromort

Micromorts are used to measure the risk inherent in various daily activities. A microprobability is a one-in-a million chance of any given event; a micromort is the microprobability of death.

For an average American, the risk of dying of unnatural causes is one in a million per day, or one minimort (1). The risk of dying under general anesthesia is five per million, or five minimorts. For COVID-19, the exact micromort value cannot yet be calculated – and it depends on many variables.

R0, a measure of microbial spread, is defined as the expected number of secondary infectious cases produced by a primary infectious case. To control an epidemic, R0 must be brought below 1. Rt (the effective reproduction number) determines the potential for epidemic spread at a specific time t under the control measures in place. Social interaction during the SARS-CoV-2 pandemic has dramatically reduced Rt in many countries (2).

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  1. DC Roberts (2020). Available at: nyti.ms/3heEiEz. 
  2. TV Inglesby, JAMA, [Epub ahead of print] (2020). PMID: 32356869.
About the Author
Ivan Damjanov

Professor Emeritus of Pathology at the University of Kansas, Kansas City, USA.

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