Subscribe to Newsletter
Outside the Lab Oncology, Training and education

The Trials of Mesothelioma

Famously linked to asbestos exposure, malignant mesothelioma (MM) is an uncommon cancer that can prove difficult to accurately diagnose. But as testing methods advance, methods for distinguishing subtypes of MM are improving – with newer antibodies becoming available for immunohistochemistry (IHC) panels, and molecular testing methods displacing IHC in some cases as the preferred method for separating benign and malignant proliferations.

Table 1. The topics covered by the 2017 malignant mesothelioma guidelines.

To provide guidance for pathologists and address the latest advances, the International Mesothelioma Interest Group has issued updated guidelines, covering a range of practical topics for pathologists looking to accurately diagnose MM (see Table 1), while also covering some of the latest advances, including predictors of prognosis and therapy response (1).

The authors caution that pathologists should not consider asbestos exposure when diagnosing the disease, but offer a notable reminder: “MM, although a rare tumor, has a grave prognosis and invariably has medicolegal implications.”

Receive content, products, events as well as relevant industry updates from The Pathologist and its sponsors.
Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

  1. AN Husain et al., “Guidelines for pathologic diagnosis of malignant mesothelioma: 2017 update of the consensus statement from the international mesothelioma interest group”, Arch Pathol Lab Med, [Epub ahead of print] (2017). PMID: 28686500.
About the Author
Roisin McGuigan

I have an extensive academic background in the life sciences, having studied forensic biology and human medical genetics in my time at Strathclyde and Glasgow Universities. My research, data presentation and bioinformatics skills plus my ‘wet lab’ experience have been a superb grounding for my role as an Associate Editor at Texere Publishing. The job allows me to utilize my hard-learned academic skills and experience in my current position within an exciting and contemporary publishing company.

Related Application Notes
Tumor Genomic Profiling with SureSelect Cancer Tumor-Specific Assays

| Contributed by Agilent

Comprehensive Genomic Profiling with SureSelect Cancer CGP Assay

| Contributed by Agilent

Preventing Bias in scRNAseq Performed on Solid Tumors

| Contributed by Revvity

Related Product Profile
Diagnostics Genetics and epigenetics
QIAseq® Pan Cancer Multimodal cuts user interventions by 50%

| Contributed by QIAGEN

Most Popular
Register to The Pathologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:
  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine

Register