Lifesaving, Blood-Typing Lab-on-a-Chip
A new, fully automated chip can type blood in five minutes
Michael Schubert | | Quick Read
In an emergency, do you know what type of blood you would need? Many don’t – and there often isn’t time to perform accurate blood typing, which requires specialized laboratory equipment and personnel. That’s why researchers from Tokyo University of Science have created a fully automated lab-on-a-chip that performs highly sensitive blood typing in just five minutes (1). The chip dilutes the blood, mixes it with air, and homogenizes it before introducing it to four reaction chambers: one each for A, B, and D antigens and a negative control. The user simply loads the blood, starts the chip, and reads the results by observing coagulation in the reaction chambers.
A lifesaver? Perhaps. Senior author Masahiro Motosuke said that the chip “will lead to the simplification of medical care in emergency situations and will greatly reduce costs and the necessary labor on parts of medical staff (2).”
- K Yamamoto et al., Biomicrofluidics, 14, 024111 (2020). PMID: 32549921.
- Tokyo University of Science (2020). Available at: bit.ly/2QlaZob.