A 32-year-old man presented with painless right ear swelling for the past eight months. There is no ear discharge or fever. PAS staining shows no fungal hyphae.
What is your diagnosis?
a. Hodgkin lymphoma
b. Angiolymphoid hyperplasia with eosinophilia
c. Parasitic infestation
d. T-cell lymphoma
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Answer to last issue’s Case of the Month… B. Choroid plexus papilloma This tumor was diagnosed as a choroid plexus papilloma, WHO Grade I, with extensive calcifications and metaplastic bone formation. Choroid plexus papillomas are rare, slow-growing, benign neoplasms that arise from choroid plexus epithelium and represent 0.3–0.8 percent of all central nervous system neoplasms. The hallmark of these tumors is a papillary architecture. Papillae are composed of cuboidal/columnar cells with basally placed nuclei recapitulating normal choroid plexus architecture (1). The presence of calcifications and ossification is an uncommon phenomenon, particularly to the extent seen in this case. Submitted by Ada Baisre, Associate Professor of Pathology and Laboratory Medicine, Rutgers-New Jersey Medical School, Newark, USA. Reference
- DN Louis et al., World Health Organization Histological Classification of Tumours of the Central Nervous System. International Agency for Research on Cancer: 2016.
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