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Outside the Lab Histology, Clinical care

Case of the Month

This malignant salivary tumor was surgically removed from the parotid gland of a 67-year-old man.

Tumors of this type express the receptors for which hormone?

a Androgen
b Estrogen
c Inhibin
d Prolactin

Click to register your guess

We will reveal the answer in next month’s issue!

Do you think you have a good case of the month? Email it to [email protected]

Answer to last issue’s Case of the Month…

C. Cytokeratin CK7

This microphotograph demonstrates the typical features of extra-mammary Paget disease. Tumor cells scattered in the epidermis have clear cytoplasm and are easily recognized even without special stains. Vulvar Paget tumor cells react typically with the antibody to CK7, which does not, however, react with the adjacent normal epithelial cells. In approximately 20 percent of extra-mammary Paget cases, tumor cells also react with the antibody to CK20.

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