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IHC markers can substitute genetic alterations for quicker diagnoses.
Soft tissue tumors are diverse with over 100 types.
Many tumors with different behaviors appear histologically similar.
IHC is cost-effective compared to NGS.
Certain IHC markers offer high specificity for specific tumors.
Pathologists should be aware of pitfalls in interpreting IHC results.
Continued education through CME is important for keeping up with IHC advancements.
