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Shifts in Influenza Activity 2018 to 2023

Influenza trends and respiratory virus co-infections showed shifts in activity patterns and age-related risks during the COVID-19 pandemic years

09/29/2025 News 2 min read

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Children under 5 have higher odds of influenza co-infection.
Study analyzed 386,283 samples from 2018-2023.
Influenza positivity peaked in 2019 with 14.4 percent.
Co-infections occurred most with rhinovirus.
Influenza activity increased post-pandemic measures.
Multiplex PCR assays expanded testing volumes significantly.
Severe acute respiratory syndrome coronavirus 2 was detected in some cases.