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The Pathologist / Issues / 2025 / September / Multiomics Improves Latestage Melanoma Survival / Summary
Oncology Precision medicine Digital and computational pathology Omics Molecular Pathology Research and Innovations

Multiomics Improves Late-stage Melanoma Survival

How a single-cell proteomics test, run on a standard pathology slide, can reshape treatment decisions

09/09/2025 Technology 4 min read
article Full Article Summary Notecard

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A recent study in Nature Medicine highlights a multiomics approach combining spatial single-cell proteomics, which significantly enhances treatment decision-making for patients with late-stage melanoma. This innovative method led to a three-fold increase in progression-free survival compared to standard treatments. The study team, including experts like Stéphane Chevrier and Andreas Wicki, addressed logistical challenges and demonstrated the potential of advanced biomarker selection for personalized therapy, while emphasizing the importance of drug access and reimbursement in integrating such diagnostics into routine care.

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