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The Pathologist / Issues / 2025 / October / Whats Causing Sudden Cardiac Death / Summary
Forensics Research and Innovations Insights

What's Causing Sudden Cardiac Death?

Autopsies reveal faulty heart valves in the majority of SCD cases

By Kathryn Wighton 10/29/2025 News 1 min read
article Full Article Summary Notecard

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Aortic regurgitation, commonly linked to a bicuspid aortic valve, has been identified as a significant cause of sudden cardiac death (SCD), associated with left ventricular remodeling and fibrosis. A recent study analyzed 8,551 SCD cases from 2014 to 2023, finding that 10 instances were primarily due to aortic regurgitation. The mean age of patients was 43, predominantly males. The study highlighted severe cardiac alterations in the AR group, stressing the need for awareness regarding its role in sudden death, particularly when tied to bicuspid valve abnormalities.

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Kathryn Wighton

Editor, Conexiant

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