SDR-seq enables simultaneous DNA and RNA analysis.
It processes up to 480 genomic loci and gene expressions per cell.
Applicable to human iPSCs and B cell lymphoma samples.
Links genetic variants to gene expression effectively.
Reveals mutation burdens correlate with tumor behavior.
Enhances understanding of cancer progression and treatment resistance.
Could improve functional phenotyping in clinical labs.
Fosters insights into complex mutational landscapes.
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