Genetics and epigenetics Omics Screening and monitoring Molecular Pathology

Same Disease, Different DNA

Study finds Chinese heart disease patients have four times more rare genetic variants than UK counterparts

10/23/2025 News 2 min read

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Study published in Precision Clinical Medicine on HCM genetics.
593 Chinese patients and 1,232 UK patients analyzed.
53 percent of Chinese patients had rare genetic variants.
Ancestry-specific variants can aid diagnostic criteria.
Genetic variant accuracy improved using Genebe platform.
Similar proportion of pathogenic variants in both populations.
Limitations in current reference databases for diverse ancestries.