HPV-DeepSeek, a next-generation liquid biopsy test, shows exceptional sensitivity (98.7 percent) and specificity (99.1 percent) for detecting HPV-related circulating tumor DNA in over 400 patients. Presented by Adam S. Fisch at the AMP 2025 meeting, the assay targets 43 HPV genotypes and has potential applications in early diagnosis, treatment monitoring, and assessment of residual disease across various cancer types, including oropharyngeal and cervical cancers, while providing insights into specific mutations and viral integration patterns.
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