Whole-Genome Sequencing Assay Detects HPV

HPV-DeepSeek assay shows 98.7 percent sensitivity, 99.1 percent specificity.

Targets 43 HPV genotypes, crucial for early cancer detection.

Study involved 224 patients with HPV-associated squamous cell carcinoma.

High median genome coverage near 100 percent in true-positive cases.

Reports PIK3CA mutations and viral integration patterns.

Observations align with established cancer-site-specific tendencies.

Potential applications in treatment monitoring and assessing residual disease.