Whole-Genome Sequencing Assay Detects HPV

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1. HPV-DeepSeek assay shows 98.7 percent sensitivity, 99.1 percent specificity.

2. Targets 43 HPV genotypes, crucial for early cancer detection.

3. Study involved 224 patients with HPV-associated squamous cell carcinoma.

4. High median genome coverage near 100 percent in true-positive cases.

5. Reports PIK3CA mutations and viral integration patterns.

6. Observations align with established cancer-site-specific tendencies.

7. Potential applications in treatment monitoring and assessing residual disease.