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The Pathologist / Issues / 2025 / November / The Fevers That Felled Napoleons Army / Summary
Microbiology & Immunology Infectious Disease Genetics and epigenetics

The Fevers That Felled Napoleon’s Army

Genomic sequencing identifies pathogens behind one of military history’s greatest medical mysteries

11/17/2025 News 2 min read
article Full Article Summary Notecard

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Research on the remains of soldiers from Napoleon's 1812 Russian retreat has uncovered genetic evidence of paratyphoid fever and relapsing fever, illnesses that likely contributed to the army's significant losses during this perilous campaign. Analyzing ancient DNA from 13 soldiers' teeth found in Vilnius, Lithuania, researchers identified Salmonella enterica (Paratyphi C) and Borrelia recurrentis, revealing how these infections paralleled historical reports of illness among troops. Though previous studies suggested other pathogens, this analysis focused on two specific bacteria, emphasizing that fatigue, malnutrition, and exposure compounded their impact.

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