Researchers at Indiana University have developed a novel multiplex real-time PCR assay that significantly speeds up the identification of Histoplasma, Blastomyces, and Coccidioides fungal infections, which are endemic in the US. Led by Kenneth Gavina, the assay can detect these pathogens directly from clinical specimens in a single run, bypassing traditional culture methods that are time-consuming. The technology, using a simplified lysis method, shows promising results, potentially leading to improved patient outcomes through faster diagnosis and treatment initiation.
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