New Hope for High-Risk MS Patients

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1. Indicators of MS can show years before clinical symptoms.

2. Myelin injury occurs around 7 years before symptoms, followed by axonal damage a year later.

3. Astrocytic changes relate to inflammation, occurring upon symptom onset.

4. Immune signaling pathway alterations noted during presymptomatic stage.

5. A candidate biomarker panel proposed for early MS detection.

6. Importance of longitudinal biobanks highlighted.

7. Potential for improved early detection and monitoring strategies.