New Hope for High-Risk MS Patients

Indicators of MS can show years before clinical symptoms.

Myelin injury occurs around 7 years before symptoms, followed by axonal damage a year later.

Astrocytic changes relate to inflammation, occurring upon symptom onset.

Immune signaling pathway alterations noted during presymptomatic stage.

A candidate biomarker panel proposed for early MS detection.

Importance of longitudinal biobanks highlighted.

Potential for improved early detection and monitoring strategies.