Microbiology and Immunology Liquid biopsy Genetics and epigenetics

Can a Blood Test Distinguish ME/CFS?

A genome-wide epigenetic blood test using chromosome conformation profiling reported high accuracy in distinguishing ME/CFS from healthy controls.

By Kathryn Wighton 11/26/2025 News 2 min read

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Study on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
Focus on chromosome conformation profiling.
Sample size: 47 patients, 61 controls.
Developed Episwitch CFS test with 200 markers.
Sensitivity: 92 percent, specificity: 98 percent, accuracy: 96 percent.
Links identified with cytokine signaling and immune pathways.
Potential for personalized treatment strategies.
Findings align with previous ME/CFS research.

About the Author(s)

Kathryn Wighton

Editor, Conexiant

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