A recent study from Johns Hopkins University reviewed 904 patients with surgically resected pancreatic neuroendocrine tumors (PanNETs) and emphasized the prognostic importance of tumor grading using the Ki-67 index. The 10-year overall survival rates varied significantly, indicating 81% for G1 tumors and only 23% for G3 tumors. Key factors influencing survival included tumor size, vascular invasion, and tumor variants like insulinomas. The study also revealed a shift towards earlier staging, highlighting advancements in early detection.
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