A Chinese bibliometric analysis examined 780 publications from 2014 to 2024, revealing oxidative stress as a key factor linking mitochondrial dysfunction to osteoporosis. Research output has consistently increased since 2016, predominantly from China and the US. Topics like apoptosis, mitophagy, and mitochondrial transfer were frequently discussed, highlighting the role of oxidative stress and cellular signaling in bone metabolism. Emerging areas of research involve ferroptosis and SIRT family proteins, with potential therapeutic strategies involving vitamin K2 and resveratrol. The study emphasizes the need for enhanced international collaboration in this domain.
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