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The Pathologist / Issues / 2025 / December / Digital PCR Opening up the Liquid Biopsy Landscape / Notecards
Oncology Liquid biopsy Precision medicine Omics Molecular Pathology

Digital PCR: Opening up the Liquid Biopsy Landscape

A sensitive, droplet-based approach for circulating tumor DNA analysis in precision oncology

By Marwan Alsarraj 12/04/2025 Discussion 3 min read
article Full Article Summary Notecard

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  1. Liquid biopsies provide a minimally invasive approach for ctDNA analysis.

  2. Traditional methods have limitations in assessing tumor heterogeneity.

  3. ddPCR enhances sensitivity and allows for precise quantification.

  4. ctDNA can inform diagnosis and treatment response.

  5. Advances in ddPCR technology support routine disease monitoring.

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About the Author(s)

Marwan Alsarraj

Marwan Alsarraj is the Global Segment Manager, Life Science Group, at Bio-Rad Laboratories. He has been at the forefront of developing, marketing, and commercializing technologies for the past 19 years in the life science research industry. Alsarraj obtained his MS in biology at the University of Texas, El Paso.

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