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The Pathologist / Issues / 2025 / Aug / Mapping Immune Markers in Rare Thymic Tumors / Notecards
Microbiology & Immunology Research and Innovations

Mapping Immune Markers in Rare Thymic Tumors

High PD-L1 expression in thymic carcinomas may support its inclusion in routine histopathologic evaluation

08/26/2025 News 1 min read
article Full Article Summary Notecard

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  1. Study focused on immune markers PD-1 and PD-L1 in TETs.

  2. 70 patients' tumor samples were analyzed.

  3. PD-1 found mostly in immune cells, PD-L1 in tumor cells.

  4. >80 percent of thymic carcinomas expressed high PD-L1.

  5. High PD-L1 linked to advanced disease stages.

  6. Need for further research on prognostic value of PD-L1.

  7. Standardization of PD-L1 testing methods is recommended.

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