The ongoing spread of H5N1 bird flu, now identified in mammals across the US, prompts the introduction of a national proficiency testing program for laboratories slated for launch in fall 2025. In a discussion led by Bobbi S. Pritt from Mayo Clinic, key challenges include differentiating H5N1 from seasonal influenza due to overlapping symptoms. Labs face diagnostic hurdles requiring reflex testing. Emphasizing the need for practical proficiency testing, workforce training, and robust data-sharing networks is vital for effective management of emerging pathogens like H5N1 to enhance public health preparedness.
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