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The Pathologist / Issues / 2025 / Aug / From Biopsy to Bedside in a Week Inside the GUSTO Trial / Summary
Oncology Clinical care Precision medicine Research and Innovations

From Biopsy to Bedside in a Week: Inside the GUSTO Trial 

Can gene expression subtyping be used to guide treatment decisions for bladder cancer?

By Helen Bristow 08/26/2025 Interview 3 min read
article Full Article Summary Notecard

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The GUSTO trial in the UK aims to tailor treatments for muscle-invasive bladder cancer (MIBC) based on genetic subtypes. Led by Jim Catto, the study involves collaboration among various healthcare teams, including pathologists and oncologists, to provide rapid gene expression results within seven days. This phase 2 trial enhances understanding of individualized care pathways and aims to inform future definitive trials. The innovative lab processes have earned recognition from the Royal College of Pathologists, underscoring the importance of academic and clinical partnerships in advancing cancer diagnostics.

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About the Author(s)

Helen Bristow

Combining my dual backgrounds in science and communications to bring you compelling content in your speciality.

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