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The Pathologist / Issues / 2022 / Dec / Cellular Spectrometry
Oncology Analytical science Microscopy and imaging Oncology

Cellular Spectrometry

An array of dazzling cells viewed using MALDI-TOF mass spectrometry

By Eva Cuypers 12/28/2022 Gallery 1 min read

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Molecular images of single cells in 2D cultures generated on a MALDI-ToF instrument. Top: fibroblasts (left) and macrophages (right); bottom: cardiomyocytes (left) and breast cancer cells (right). Inset: a zoom in on a single breast cancer cell showing the different levels (blue, green, red) of phosphatidylcholine 36:1 in the cell. Scale bars are 200 μm; inset scale bar is 50 μm.

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About the Author(s)

Eva Cuypers

Assistant Professor of Imaging Mass Spectrometry in Peri-Operative Diagnostics at Maastricht MultiModal Molecular Imaging Institute, Maastricht, The Netherlands.

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