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The Pathologist / Issues / 2021 / Oct / Removing Race from the Diagnostic Equation
Guidelines and Recommendations Screening and monitoring Clinical care

Removing Race from the Diagnostic Equation

New recommendations aim to reduce racial health disparities in diagnosing kidney disease

By Liv Gaskill 10/19/2021 Quick Read (pre 2022) 1 min read

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To reduce racial health disparities, researchers have suggested a new approach for estimating kidney function that removes race from the equation (1). “Our research showed that if you use a blood cystatin C test instead of a blood creatinine test, you don’t need to include race to get a similarly accurate estimate of kidney function,” said Alan S. Go, co-senior author on the study (2).

The results have informed the National Kidney Foundation and the American Society of Nephrology Task Force’s final report on diagnosing kidney disease without a race variable (3). Within the report, the group recommends use of the new eGFR 2021 CKD EPI creatinine equation while increasing use of cystatin C combined with serum creatinine to confirm glomerular filtration rate or kidney function assessment.

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References

  1. CY Hsu et al., N Engl J Med, [Online ahead of print] (2021). PMID: 34554660.
  2. S Rochman, H Tremblay (2021). Available at: https://k-p.li/3iCOIRl.
  3. C Delgado et al., Am J Kidney Dis, 78, 103 (2021). PMID: 33845065.

About the Author(s)

Liv Gaskill

During my undergraduate degree in psychology and Master’s in neuroimaging for clinical and cognitive neuroscience, I realized the tasks my classmates found tedious – writing essays, editing, proofreading – were the ones that gave me the greatest satisfaction. I quickly gathered that rambling on about science in the bar wasn’t exactly riveting for my non-scientist friends, so my thoughts turned to a career in science writing. At Texere, I get to craft science into stories, interact with international experts, and engage with readers who love science just as much as I do.

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