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April 2016
Welcome to the April issue. In our Upfront topics, you’ll find bacterial biomarkers, direct-to-consumer lab tests, and single-gene sources of disease. Our Feature asks whether the epithelial-to-mesenchymal transition is necessary for metastasis – and if not, what it does instead. In Practice explores the potential of next generation tissue microarrays. Superbugs and similarities in protein complexes fill our NextGen section, and Profession profiles the growth of Eastern Europe’s largest private pathology lab. We Sit Down With Suzy Lishman, President of the Royal College of Pathologists and a consultant cellular pathologist at Peterborough City Hospital.
The PDAC Key
April 26, 2016
Pancreatic cancer cells don’t seem to rely on EMT for metastasis – but it plays a key role in their ability to resist our best chemotherapy options
1 min read
Tracking the Transition
April 26, 2016
A triple-transgenic mouse model allows researchers to trace the lineage of EMT tumor cells, and reveals the transition’s surprising lack of significance in metastasis
1 min read
No Regrets
April 22, 2016
Sitting Down With… Suzy Lishman, President of the Royal College of Pathologists (RCPath) and a consultant cellular pathologist at Peterborough City Hospital, UK.
1 min read
Pilsen’s Second-Biggest Export: Pathology
April 22, 2016
From plastic beer case furniture to the largest pathology laboratory in Eastern Europe
1 min read
Listen to your Gut
April 22, 2016
Recent studies reveal that the organizational protein complexes in gut microvilli closely resemble those of ear stereocilia – so what does this mean for genetic disorders of either?
1 min read
A Kryptonite for Pathogens
April 22, 2016
Could antibiotics that target virulence factors be the key to defeating multi-drug resistant “bugs of steel?”
1 min read
The Core of the Problem
April 22, 2016
Next generation tissue microarrays overcome punching inaccuracies and bring the technique into the era of precision medicine
1 min read
Proceed With Caution
April 22, 2016
Two recent studies on EMT may revise the field’s understanding of the process – but it’s important to keep in mind both the breakthroughs and the limitations of the work
1 min read
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