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December 2022 Issue of The Pathologist

In the final issue of The Pathologist for 2022, we explore how genomic medicine is creating a rare disease “revolution.” Learn how genomics is progressing at rocket speed; why rapid, reliable, and accessible sequencing is life-changing for patients; and just how AI and awareness fit into this quickly evolving picture. Also in this issue, we hear how The University of Texas Medical Branch is working to solve dwindling access for benign hematology patients, why pathologists need to talk about tech, and how overcoming lung cancer treatment resistance requires predictive biomarkers. And it doesn’t stop there: the importance of the phlebotomist’s poke plan; existing AI in the lab; preparing for another pandemic; and Sitting Down With… Julie Feldstein, Chief Pathologist at HistoWiz, on the jump from academia to industry.

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Articles featured in this issue

Outside the Lab Training and education

Assessing Pathology Knowledge

| Fred Bosman | 2 min read

Extended matching questions ensure that pathology students understand the material – not just how to pass a test

Diagnostics Liquid biopsy

Plasma Mutation Profiling

| George Francis Lee

Can a “plasma-first” approach to biopsy result in better testing for lung cancer?

Diagnostics Genetics and epigenetics

Growth in Cancer Genetics

| George Francis Lee | 2 min read

The world of cancer genetics is getting bigger… so we bring you the latest news and research in molecular oncology

Inside the Lab Technology and innovation

Faster Than a Speeding Biopsy

| George Francis Lee

Multi-cancer early detection technology is allowing us to detect undiagnosed cancer earlier than ever before

Diagnostics Genetics and epigenetics

The Genes of the Spectrum

| George Francis Lee | 2 min read

How is current research mapping a fuller picture of the autism spectrum?

Diagnostics Genetics and epigenetics

The Architecture of ADHD

| Liv Gaskill | 2 min read

ADHD subgroups are characterized by age at first diagnosis – but are they underpinned by different genetic etiologies?

Diagnostics Omics

By Our Powers Combined…

| George Francis Lee

By uniting three medical disciplines, can we predict the effectiveness of non-small cell lung cancer treatment?

Subspecialties Hematology

A Space Waiting to Be Filled

| Caitlin Raymond, Paul Young, Christopher Zahner | 3 min read

Benign hematology patients are suffering from a lack of available professionals – can pathologists help?

Inside the Lab Digital and computational pathology

Pathologists, We Need to Talk About Tech

| Dean Bitan | 4 min read

In an aging world with cancer cases increasing, it’s time for technology

Outside the Lab Profession

The Ultimate Influencer

| E. Blair Holladay | 2 min read

Laboratory leadership is evident – both on social media and in real life

Diagnostics Omics

A Rare Disease Revolution

| Stephen Kingsmore | 15 min read

Rapid, reliable, widespread whole genome sequencing could shorten the rare disease diagnostic odyssey and improve patients’ lives

Inside the Lab Bioinformatics

This Time, It’s Personal

| Ofer Sharon | 5 min read

Overcoming lung cancer treatment resistance requires predictive biomarkers that take into account patient variability

Subspecialties Microbiology and immunology

Resisting the Resistance

| Nick Arab | 4 min read

The drug resistance crisis is becoming an increasing burden to healthcare systems – could rapid phenotypic testing help?

Diagnostics COVID-19

Fail to Prepare, Prepare to Fail

| Emma Hannay, Karishma Saran | 6 min read

Are global health systems ready for another pandemic – or have we failed to learn our lesson from COVID-19?

Inside the Lab Technology and innovation

The AI You’ve Never Considered

| Nathan Buchbinder | 4 min read

AI process automation solutions are thriving in the lab – but many examples are flying under the radar

Inside the Lab Technology and innovation

A Personal Touch to Cancer Screening

| Tim Simpson | 3 min read

AI has the potential to transform personalized cancer screening – but there are challenges we must first overcome

Outside the Lab Profession

(Blood) Drawing on Experience

| Liv Gaskill | 13 min read

Sampling procedures can invoke anxiety and fear in many patients, but taking simple steps can establish a positive patient experience

Outside the Lab Profession

From Academia to Industry

| Michael Schubert | 5 min read

Julie Feldstein outlines her career trajectory and offers tips for pathologists with an interest in industry

Other issues of 2022