personalized, responsive service and to improve the site, we remember and store information about how you use
In this issue we explore how environmental factors from decades ago can have a profound impact on gene expression today. Focusing on the Dutch Hongerwinter of 1944, Mary J. Wirth examines the unusually high prevalence of heart disease and metabolic disorders that children of the era exhibit, and asks whether we can manipulate our epigenome to live longer, healthier lives. Also in the December issue, read about compounds that inhibit the aggregation of a protein linked to Parkinson’s disease, the evolution of epigenetic biomarkers, and how to succeed in collaboration and communication. We also sit down with Wendy L. Frankel, Kurtz Chair and Distinguished Professor of Pathology and Chair of the Department of Pathology at The Ohio State University Wexner Medical Center, Columbus, USA.