Cookies

Like most websites The Pathologist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.

December 2015 Issue of The Pathologist

“Welcome to the December issue. Our upfront topics range from an investigation of the “dark virome”, to a 3D printed plastic microscope for quick and inexpensive blood counts. Our Feature looks at the huge challenge pancreatic ductal adenocarcinoma poses and the perseverant researchers on a mission to improve survival rates. In Practice features Raman spectroscopic imaging for powerful cell analysis, and in Next Gen we benchmark amyotrophic lateral sclerosis. In profession, Peter Chimkupete recounts his experiences mentoring African laboratories in order to improve quality standards, and we Sit Down With Michael Wells, Emeritus Professor of Gynecological Pathology, University of Sheffield Medical School, UK, and Past President of the European Society of Pathology.”

Register to download

Register here to download any issue of The Pathologist for FREE.

Login

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine
Register

Or Login via Social Media

By clicking on any of the above social media links, you are agreeing to our Privacy Notice.

Articles featured in this issue

Inside the Lab Digital and computational pathology

Show Me the Money!

| Fedra Pavlou

Wanting to go digital, but struggling with justification? Do not fear, help will soon be at hand...

Diagnostics Genetics and epigenetics

The Dark Virome

| Roisin McGuigan

Over 90 percent of the human cutaneous virome is made up of unclassifiable “dark matter”

Inside the Lab Oncology

Driving Discovery

| Roisin McGuigan

A big data approach to cancer driver genes yields insights into how these mutations affect protein interaction

Inside the Lab Oncology

Illuminating Idiopathic Cytopenias

| Roisin McGuigan

Genetic testing could shed light on unexplained low blood counts

Subspecialties Oncology

Demystifying Metastasis

| Roisin McGuigan

Integrin expression by tumor exosomes could help oncologists pinpoint which patients will present with metastatic disease – and to which organs

Subspecialties Oncology

A Crystal Ball for Cancer Spread?

| Roisin McGuigan

αB-crystallin expression could identify breast cancer patients at risk of developing brain metastasis.

Outside the Lab Hematology

Multitalented Marker

| Roisin McGuigan

Cardiac troponin can be used as an independent early indicator of end-stage kidney disease, and death, new study suggests

Diagnostics Hematology

Plastic Pays

| Roisin McGuigan

An all-plastic microscope for fast staining and analysis of white blood cells could allow cheap, point-of-care blood work

Subspecialties Neurology

What’s in a Name?

| Sanja M. Milenkovic

Can we accept meningothelial hyperplasia as a true preneoplastic proliferative?

Inside the Lab Regulation and standards

Be Ready for IQCP

| Sharon Ehrmeyer

What is "The Individual Quality Control Plan (IQCP)" and should test sites adopt it?

Subspecialties Oncology

Mission: Impossible

| Michael Schubert

Pancreatic cancer is tough to understand, diagnose and treat. Undeterred researchers are on a quest to crack the case.

Diagnostics Oncology

Tapping a Rich Vein

| Christopher Chapman

Circulating tumor cells may hold information crucial for better pancreatic cancer diagnosis and treatment – but locating them needs special tactics

Diagnostics Oncology

New Ab-ilities in Imaging

| Michael Schubert

Pancreatic cancer is a challenge to stage because there’s no good molecular imaging method – but three new antibody conjugates may change that

Diagnostics Oncology

Surprising Subtypes

| Michael Schubert

Pancreatic cancer is often treated as a homogeneous disease, but new research reveals distinct subtypes of tumor and stromal gene expression

Outside the Lab Oncology

Friend or Foe?

| Anne Marie Lennon

Screening for pancreatic cysts can help with early detection and treatment – but how can we tell which lesions are benign and which may progress to cancer?

Subspecialties Oncology

(Chemo)resistance Is Futile

| Michael Schubert

Epithelial-to-mesenchymal transition in pancreatic cancer may play a role in treatment resistance.

Subspecialties Oncology

Breaching Cancer’s Defenses

| Ingunn Stromnes

A new immunotherapy approach shows that engineered T cells are able to penetrate into pancreatic tumors and directly attack the cancer

Diagnostics Oncology

An Epigenetic Epiphany

| Michael Schubert

When genetics yielded unsatisfactory answers about pancreatic cancer’s persistent survival, researchers looked beyond the genome – and found telling epigenetic changes

Diagnostics Oncology

Building a Better Mousetrap

| Michael Schubert

It’s often difficult to target pancreatic cancer cells while sparing healthy tissue – but a new therapy concept not only makes this possible, but also enhances the potential effectiveness of adjuvant treatments

Diagnostics Oncology

A New Dimension in Biomarker Research

| Xia-Jun Ma

RNA in situ hybridization offers a new way to overcome the challenges of advancing RNA cancer biomarkers to the clinic

Diagnostics Oncology

Portrait of a Dying Cell

| Katherine Lau

Confocal Raman microscopy is a new, noninvasive way of obtaining morphological and chemical information about cells that may lead to better cancer research

Inside the Lab Microbiology and immunology

Killing Cancer From the Inside

| Kathryn Largue, Daniel M. Davis

New super-resolution microscopy techniques give us better insight into how our immune cells fight cancer, and how we can help

Inside the Lab Neurology

Benchmarking Amyotrophic Lateral Sclerosis

| Roisin McGuigan

What does analysis of the last five years of the literature on ALS tell us about the priorities of the field, and the major contributors to it?

Outside the Lab Profession

An African Alliance

| Peter Chimkupete

UK lab medicine experts team up with their counterparts in Africa to improve testing outcomes.

Inside the Lab Profession

Track or Treat?

| Shane Brown

Considering the impact of the consumer health revolution on pathology

Diagnostics Profession

Plus Ça Change!

| Roisin McGuigan

We Sit Down With Michael Wells, Past President of the European Society of Pathology.

Other issues of 2015