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In October’s issue of The Pathologist, three experts gather to discuss the potential impact of precision profiling on the oncology landscape. How does it affect pathologists and laboratory medicine professionals in cancer care? What does it mean for guiding treatment decisions? And what does the future hold for diagnostic and prognostic medicine? Also in this issue: read about the importance of spatial biomarkers for improving immunotherapy outcomes, broaden your understanding of filarial disease, and discover how coffee is more than just coffee in Albanian laboratories. We also sit down with Gary Procop, Director of Molecular Microbiology, Virology, Mycology and Parasitology, and Vice Chair of Pathology Education at Cleveland Clinic, Ohio, USA.