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October 2020 Issue of The Pathologist

In October’s issue of The Pathologist, three experts gather to discuss the potential impact of precision profiling on the oncology landscape. How does it affect pathologists and laboratory medicine professionals in cancer care? What does it mean for guiding treatment decisions? And what does the future hold for diagnostic and prognostic medicine? Also in this issue: read about the importance of spatial biomarkers for improving immunotherapy outcomes, broaden your understanding of filarial disease, and discover how coffee is more than just coffee in Albanian laboratories. We also sit down with Gary Procop, Director of Molecular Microbiology, Virology, Mycology and Parasitology, and Vice Chair of Pathology Education at Cleveland Clinic, Ohio, USA.

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Articles featured in this issue

Outside the Lab Profession

False Negatives

| Michael Schubert

As the calls for widespread COVID-19 testing increase, so too do fake over-the-counter tests – and results

Inside the Lab Precision medicine

Prognostic Tumor Gene Test for Ovarian Cancer

| Liv Gaskill

A tumor gene test has been developed that may predict poor survival in patients with ovarian cancer

Diagnostics Biochemistry and molecular biology

Journey to Molecular Pathology

| Michael Schubert

A timeline of key molecular pathology events, from Sanger sequencing to 100,000 genomes

Diagnostics Screening and monitoring

Research Review

| Michael Schubert

What’s new in the world of pathology and laboratory medicine? We offer a rapid roundup of recent research

Diagnostics Histology

Case of the Month

A 70-year-old woman with multiple medical problems presented with abdominal pain – but what is the most likely diagnosis?

Diagnostics Analytical science

Breath Testing for Early Diagnosis

| Jonathan Lawson

Exhaled particles are of greater interest than ever – so how can we turn them to our advantage for disease diagnosis?

Inside the Lab Precision medicine

Spatial Biomarkers and Immunotherapy Response

| Cliff Hoyt

To improve immunotherapy outcomes, we need to explore new biomarkers that offer spatial resolution in the tumor microenvironment

Inside the Lab Precision medicine

Precision Medicine and the Patient Journey

| E. Blair Holladay

How precision medicine is expanding the laboratory’s role – and its responsibilities – in patient care

Inside the Lab Precision medicine

Precision Profiling and its Promise for Pathology

| Michael Schubert

An expert roundtable on the future of molecular medicine in pathology

Diagnostics Microbiology and immunology

Pathology’s Best-Kept Secret

| Sponsored by Q2 Solutions

Clinical trials offer pathologists the opportunity to work at the forefront of diagnostic discovery

Subspecialties Microbiology and immunology

The Problem of Filarial Disease

| Harsh Mohan, Poonam Bhaker

Harsh Mohan and Poonam Bhaker review the features and diagnosis of common filarial diseases

Diagnostics Omics

A Tipping Point for Comprehensive Genomic Profiling in Cancer

| Cindy Perettie

Precision medicine is key to every aspect of modern oncology – and comprehensive genomic profiling can help

Outside the Lab Profession

Peer-to-Peer, with Vijay Joshi

| Megha Joshi, Vijay Joshi

Megha Joshi interviews Vijay Joshi on his long and storied career as a pediatric pathologist

Outside the Lab Profession

When Coffee Is More Than Just Coffee

| Susan Oupadia

Susan Oupadia describes the challenges and rewards of two years spent building a pathology service in Albania

Outside the Lab Profession

The Laboratory Leader

| Luke Turner

We discuss laboratory testing, COVID-19, and future recruitment with laboratory leader Gary Procop

Other issues of 2020