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September 2021 Issue of The Pathologist

In September’s issue of The Pathologist, we put pathology under the microscope and ask whether its visibility – or lack thereof – in the medical school curriculum is harming its recruitment efforts. Speaking with two professors of pathology and two medical students, we ask – where exactly is pathology going wrong? Who can help to redefine pathology’s place in the curriculum? And how? Also in this issue: an open letter to medical students about pathology, the mast cell mechanisms behind allergic reactions to the COVID-19 vaccine, and an interview with Timothy Garrett, Director of Experimental Pathology and Associate Professor, Department of Pathology, Immunology and Laboratory Medicine, University of Florida, USA.

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Articles featured in this issue

 Diagnostics Genetics and epigenetics

CRISPR/Cas9 That’s Out of This World

| Liv Gaskill

A CRISPR/Cas9 genome editing tool has been developed for testing DNA damage entirely in space
Outside the Lab Profession

The 2021 Power List in Numbers

| Liv Gaskill

Breaking down this year’s Power List by country, gender, and nominations
Diagnostics Microscopy and imaging

(AI) Skin in the Game

| Michael Schubert

A new convolutional neural network system may lead to faster, easier diagnosis of skin disorders such as epidermolysis bullosa acquisita
Diagnostics Screening and monitoring

Screened at Birth

| Liv Gaskill

Advances in metabolomics may improve clinical screening for inborn errors of metabolism at birth
Diagnostics Microbiology and immunology

A Gut (Microbiome) Feeling

| Liv Gaskill

Distinctive characteristics in the gut microbiome may serve as novel biomarkers for autism spectrum disorders
Subspecialties Neurology

Expanding the Framework for Neurodegenerative Disease Diagnosis

| Michael Schubert

Adding new biomarkers to existing tests could give us a better view of the brain and the degenerative diseases that affect it
Diagnostics Screening and monitoring

Check-In Time for Cancer Screening

| Matt McManus

As the world moves on from the initial pandemic response, we urgently need to support the return of routine cancer screening and monitoring
Diagnostics Genetics and epigenetics

Next-Generation Sequencing: The Next Microscope

| Brandon S. Sheffield

Brandon S. Sheffield shares his experience with onboarding in-house NGS testing – and why he thinks everyone should follow suit
Outside the Lab Training and education

Dear Medical Students

| Matt DeJong

One medical student shares a revelation – that pathology is a specialty for all physicians
Outside the Lab Profession

COVID-19 at the Border: Lives Hanging in the Balance

| Drew Bernhisel

As the healthcare situation for detainees at the US–Mexico border deteriorates, all medical professionals have a responsibility to help
Inside the Lab Clinical care

Scientific Detectives for Better Patient Care

| E. Blair Holladay

Patients are more interested and involved than ever in their healthcare journeys – but they need the lab to act as a guide along the way
Diagnostics Biochemistry and molecular biology

Spatial Biology: Transforming Immuno-Oncology Research

| Sponsored by Lunaphore Technologies

Harnessing the potential of spatial biology to find prognostic biomarkers in melanoma patients and improve outcomes
Outside the Lab Clinical care

Meet the Humble Mast Cell

| Lakiea Wright

Are mast cell disorders playing a role in allergic reactions to COVID-19 vaccines? Lakiea Wright demystifies these cells and their behavior
Subspecialties Neurology

Studying Brains on a Lab Bench

| James Ross

Monitoring epileptic and amyotrophic lateral sclerosis neural networks in vitro with microelectrode array technology
Inside the Lab Microscopy and imaging

A Place for Everything in Spatial Biology

| Nachiket Kashikar

A guide to understanding – and implementing – spatial biology in the pathology lab
Subspecialties Profession

Macroscopists and Cytotechnicians: The Pathologist’s Counterparts

| Hatice Beşeren

Hatice Beşeren introduces us to the laboratory professionals who help keep Turkey’s pathology services running
Diagnostics Analytical science

Interrogating Metabolism

Sitting Down With… Timothy Garrett, Director of Experimental Pathology and Associate Professor, University of Florida, USA

Other issues of 2021