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September 2021 Issue of The Pathologist

In September’s issue of The Pathologist, we put pathology under the microscope and ask whether its visibility – or lack thereof – in the medical school curriculum is harming its recruitment efforts. Speaking with two professors of pathology and two medical students, we ask – where exactly is pathology going wrong? Who can help to redefine pathology’s place in the curriculum? And how? Also in this issue: an open letter to medical students about pathology, the mast cell mechanisms behind allergic reactions to the COVID-19 vaccine, and an interview with Timothy Garrett, Director of Experimental Pathology and Associate Professor, Department of Pathology, Immunology and Laboratory Medicine, University of Florida, USA.

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Articles featured in this issue

Diagnostics Genetics and epigenetics

CRISPR/Cas9 That’s Out of This World

| Olivia Gaskill

A CRISPR/Cas9 genome editing tool has been developed for testing DNA damage entirely in space

Outside the Lab Profession

The 2021 Power List in Numbers

| Olivia Gaskill

Breaking down this year’s Power List by country, gender, and nominations

Diagnostics Microscopy and imaging

(AI) Skin in the Game

| Michael Schubert

A new convolutional neural network system may lead to faster, easier diagnosis of skin disorders such as epidermolysis bullosa acquisita

Diagnostics Screening and monitoring

Screened at Birth

| Olivia Gaskill

Advances in metabolomics may improve clinical screening for inborn errors of metabolism at birth

Diagnostics Microbiology and immunology

A Gut (Microbiome) Feeling

| Olivia Gaskill

Distinctive characteristics in the gut microbiome may serve as novel biomarkers for autism spectrum disorders

Subspecialties Neurology

Expanding the Framework for Neurodegenerative Disease Diagnosis

| Michael Schubert

Adding new biomarkers to existing tests could give us a better view of the brain and the degenerative diseases that affect it

Diagnostics Screening and monitoring

Check-In Time for Cancer Screening

| Matt McManus

As the world moves on from the initial pandemic response, we urgently need to support the return of routine cancer screening and monitoring

Diagnostics Genetics and epigenetics

Next-Generation Sequencing: The Next Microscope

| Brandon S. Sheffield

Brandon S. Sheffield shares his experience with onboarding in-house NGS testing – and why he thinks everyone should follow suit

Outside the Lab Training and education

Dear Medical Students

| Matt DeJong

One medical student shares a revelation – that pathology is a specialty for all physicians

Outside the Lab Profession

COVID-19 at the Border: Lives Hanging in the Balance

| Drew Bernhisel

As the healthcare situation for detainees at the US–Mexico border deteriorates, all medical professionals have a responsibility to help

Inside the Lab Clinical care

Scientific Detectives for Better Patient Care

| E. Blair Holladay

Patients are more interested and involved than ever in their healthcare journeys – but they need the lab to act as a guide along the way

Outside the Lab Clinical care

Meet the Humble Mast Cell

| Lakiea Wright

Are mast cell disorders playing a role in allergic reactions to COVID-19 vaccines? Lakiea Wright demystifies these cells and their behavior

Subspecialties Neurology

Studying Brains on a Lab Bench

| James Ross

Monitoring epileptic and amyotrophic lateral sclerosis neural networks in vitro with microelectrode array technology

Inside the Lab Microscopy and imaging

A Place for Everything in Spatial Biology

| Nachiket Kashikar

A guide to understanding – and implementing – spatial biology in the pathology lab

Subspecialties Profession

Macroscopists and Cytotechnicians: The Pathologist’s Counterparts

| Hatice Beşeren

Hatice Beşeren introduces us to the laboratory professionals who help keep Turkey’s pathology services running

Diagnostics Analytical science

Interrogating Metabolism

Sitting Down With… Timothy Garrett, Director of Experimental Pathology and Associate Professor, University of Florida, USA

Other issues of 2021