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September 2017 Issue of The Pathologist

In our September 2017 issue, Michael Laposata explores the issues that can prevent fast and accurate diagnosis, including medical errors, unnecessary testing, and professional misunderstandings. The potential cure? The diagnostic management team. We also look at a pen for non-destructive identification of tumor tissue, retirement alternatives for pathologists, precision medicine in ocular cancer, and the importance of pathologists as leaders. Finally, we sit down with Rojeet Shrestha, a rising star in clinical chemistry with a special interest in cardiometabolic disease.

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Articles featured in this issue

Outside the Lab Profession

The Sound of One Hand Clapping

| Michael Schubert

Speaking up for yourself is valuable – but only if you have an audience

Diagnostics Histology

Case of the Month

This liver disease is most often associated with the mutation of which gene?

Inside the Lab Point of care testing

Paper Trails

| Roisin McGuigan

A test powered by your fingertips could bring useful diagnostic tests to low resource settings

Inside the Lab Genetics and epigenetics

Delving into the Dark Code

| Michael Schubert

Genome exploration tool Orion digs into non-coding regions for disease-causing mutations

Diagnostics Point of care testing

TRI a New Kind of Spectrometer

| Michael Schubert

An inexpensive, smartphone based device could offer a wide range of point-of-care tests

Outside the Lab Oncology

The Trials of Mesothelioma

| Roisin McGuigan

The International Mesothelioma Interest Group has issued updated guidelines for diagnosis

Diagnostics Clinical care

Random Acts of Kinase

| Michael Schubert

A newly validated clinical assay can detect gene fusions that lead to cancer

Subspecialties Microscopy and imaging

No Lens, No Problem

| Michael Schubert

Holographic lens-free microscopy can image thick tissue samples simply and inexpensively

Diagnostics Oncology

Writing Off Cancer

| Joanna Cummings

When it comes to identifying cancerous tissue, is the “MasSpec Pen” mightier than the sword?

Outside the Lab Training and education

The Transformed Pathologist

| Byron Barksdale

Patients benefit when all physicians improve their clinical knowledge and communication skills

Outside the Lab Profession

Stepping Stones to Retirement

| Charles van Heyningen

There is more than one way to conclude a long and rewarding career

Inside the Lab Point of care testing

Good on Paper

| Andres Martinez

As we develop new point-of care diagnostics for resource limited settings, the humble sheet of paper has a lot to offer...

Outside the Lab Profession

Curing Our Diagnostic Disorder

| Michael Laposata

Could the diagnostic management team be a panacea to medical error and professional misunderstandings?

Outside the Lab Profession

The Diagnostic and Management Autopsy

| Michael Laposata

What is the diagnostic and management autopsy and why is it needed?

Inside the Lab Oncology

Keeping up with Precision Medicine

| Ruth Steer

How specialized next-gen sequencing is giving ocular cancer patients access to targeted therapies

Subspecialties Omics

Lost in Post-Translation

| Evan Y. Snyder

How can studying the molecular response to lithium help us understand and treat bipolar disorder?

Diagnostics Genetics and epigenetics

HRD Times

| Arielle Heeke

Homologous recombination deficiency plays a role in many tumors. Why hasn’t it been explored further?

Outside the Lab Training and education

Leading the Way

| Sandip SenGupta

Pathologists need to take on the challenge of leadership or risk losing their value

Outside the Lab Biochemistry and molecular biology

The Cardiometabolic Chemist

| Michael Schubert

Rojeet Shrestha, Researcher at the Faculty of Health Sciences, Hokkaido University, Sapporo, Japan

Other issues of 2017