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July 2019 Issue of The Pathologist

In this month’s issue, our gallery special feature makes its return with some of the weird and wonderful artwork that lights up the laboratory. From stunning slide images to abstract digital representations, we celebrate the visual nature of pathology and laboratory medicine by showcasing your best submissions. In addition, Alessandro Lugli explores the potential of tumor budding as a novel histopathological biomarker, Aadil Ahmed and Kamran Mirza make the case that pathology should be considered a clinical discipline, and Richard Levenson discusses the lessons he has learned throughout a successful career in the lab. We also sit down with David Wilbur, Former Director of Cytopathology and Clinical Imaging at Massachusetts General Hospital and current Chief Medical Scientist at Corista LLC, USAK.

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Articles featured in this issue

Diagnostics Histology

Case of the Month

Can you diagnose this 77-year-old man who presented with an arcuate, erythematous patch on his lower back?

Inside the Lab Microscopy and imaging

From the Ridiculous to the Sublime

| Michael Schubert

Our gallery showcase is about more than just publishing pretty pictures – it highlights art’s vital importance in a visual discipline.

Subspecialties Microbiology and immunology

A Meaningful Microbiome

| Michael Schubert

The microbial diversity and species distribution of the cervix may help diagnosticians determine the patients at increased risk of cervical cancer.

Diagnostics Omics

A Microbial Map to Cancer

| Michael Schubert

A new study uses machine learning to perform meta-analysis of eight metagenomic studies linking gut microbial signatures with colorectal cancer.

Outside the Lab Point of care testing

To POCT or Not to POCT?

| Michael Schubert

Many previously laboratory-based tests now have rapid and reliable POCT alternatives – and primary care providers should be encouraged to use them.

Diagnostics Companion diagnostics

Welcome to Our Kitchen

| David L. Rimm

David Rimm challenges the sensitivity and reproducibility of a new assay for PD-L1 detection.

Diagnostics Companion diagnostics

Improving Patient Outcomes

| Eslie Dennis, Eric Walk, Ken Bloom, Mark Kockx

A response to David Rimm’s letter that supports the role of PD-L1 testing in improving outcomes for cancer patients.

Inside the Lab Laboratory management

Fostering Quality

| E. Blair Holladay

No investment is more important for laboratory quality and patient care than investment in laboratory personnel.

Subspecialties Microscopy and imaging

The Picture of Health

| Michael Schubert

From stunning slide images to abstract representations of bodily functions, discover pathology and laboratory medicine’s most enticing visuals.

Subspecialties Histology

The Heavy Cavalry of Colorectal Cancer

| Alessandro Lugli

What is tumor budding – and how can this novel histopathological biomarker better stratify colorectal cancer patients?

Inside the Lab Liquid biopsy

CTCs in a Spin

| Luke Turner

A microfluidic device reveals new insights into the function of circulating tumor cells, providing vital information on how cancers metastasize.

Diagnostics Liquid biopsy

Fine-Tuning Immunotherapy

| George Karlin-Neumann

Techniques like droplet digital PCR technology can assist with early monitoring of cancer immunotherapy to ensure the right treatment for each patient

Outside the Lab Clinical care

Pathology: A Clinical Specialty

| Aadil Ahmed, Kamran Mirza

Pathology and laboratory medicine are clinical disciplines, and our knowledge and functions are valuable to every field of medicine.

Outside the Lab Profession

Lessons Learned, with Richard Levenson

| Richard Levenson

A leader in microscopy, imaging, and diagnostics shares the lessons he has learned over a varied and exciting career.

Inside the Lab Training and education

Revamping the Digital Interface

| Luke Turner

We sit down with digital pathology advocate David Wilbur to discuss how the advancement of digital interfaces could lead to widespread adoption.

Other issues of 2019