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July 2017 Issue of The Pathologist

Our July 2017 issue explores the issues and opportunities posed by biobanking – and two experts explain why pathology is poised to play a key role as tissue archivists and curators. We also look at an alternative to robotic microscopy, the technique of “slide-free histology”, the current state of CRISPR/Cas gene editing, and a new test for predicting which preterm infants are at highest risk of bronchopulmonary dysplasia. Finally, we sit down with Eleftherios Diamandis, a cancer biomarker guru and the discoverer of kallikreins.

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Articles featured in this issue

Outside the Lab Profession

Getting it Right First Time

| Fedra Pavlou

Can pathologists and clinicians work together more closely to reduce the number of incorrect medical assessments?

Diagnostics Histology

Case of the Month

What is the most likely diagnosis for this kidney biopsy specimen from a 22-year-old woman?

Diagnostics Oncology

Methyl Markers

| Michael Schubert

Epigenetics may predict the risk of developing anal cancer

Diagnostics Biochemistry and molecular biology

The Testing Trinity

| Michael Schubert

A blood test that can predict treatment response and reveal evolving resistance in prostate cancer

Subspecialties Microbiology and immunology

Inside Intestinal Disease

| Sheena Cruickshank

How can gut mucus microbiota lead to earlier diagnosis, or even prediction, of IBD?

Outside the Lab Oncology

Battling Blood Cancer

| Michael Schubert

The FDA authorizes a new test for blood cancers, and establishes “special controls” for future tests

Diagnostics Technology and innovation

What Lies Beneath

| Michael Schubert

A simple new method to decrease speckle noise could make OCT a valuable virtual biopsy tool

Outside the Lab Clinical care

Autopsy on Autopilot

| Guy Rutty and Bruno Morgan

When it comes to investigating death, we must first ask ourselves, “What is the question?”

Inside the Lab Digital and computational pathology

Rebuilding the Microscope for Digital Pathology

| Guoan Zheng

Expensive robotic microscopy is a barrier to digital pathology – but a new approach may be the solution

Outside the Lab Digital and computational pathology

Educating the Digital Generation

| Eduardo Alcaraz

Facing the challenges of new technologies could change the face of medical training

Inside the Lab Histology

(Bio) Banking on Pathology’s Future

| Fay Betsou

Biobanks are vital to research and diagnostics, but we still have a lot of work to do...

Inside the Lab Histology

The Promise of Precision Pathology

| Michael H.A. Roehrl

Pathologists must drive the future of precision medicine – and a new kind of pathology will be crucial

Outside the Lab Digital and computational pathology

How We Are Going Digital

| Melanie Barker and Jane Fitzpatrick

NHS Wales Health Collaborative shares the story of Wales’ ongoing transition to digital pathology

Diagnostics Genetics and epigenetics

A Clean (Gene) Break

| Michael Schubert

CRISPR/Cas gene editing is a powerful, ever-evolving tool – but it seems to be here to stay…

Inside the Lab Histology

Seeing the Light

| Michael Schubert

Conventional histopathology has drawbacks - could light-sheet microscopy change the game?

Diagnostics Clinical care

Babies’ Breath

| Jegen Kandasamy

Research reveals a potential predictor of bronchopulmonary dysplasia risk in preterm infants

Outside the Lab Profession

Time to Get Political

| Michael Schubert

Grassroots politics can promote and protect pathology through advocacy and education

Outside the Lab Oncology

Kallikrein Dream

| Roisin McGuigan

Eleftherios P. Diamandis, Hold ’em for Life Chair in Prostate Cancer Biomarkers, University of Toronto.

Other issues of 2017