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June 2019 Issue of The Pathologist

This month, we investigate the diversity problem plaguing genomic research. Although precision medicine offers great promise for diagnosing and treating disease based on an individual’s genetic background, the underrepresentation of minority groups is threatening its wider potential. Melinda Mills and Rick Kittles offer their thoughts on the scale of the problem and the action we can take to increase representation. In addition, Jesse McCoy explains the integral role that pathologists’ assistants play in the lab medicine team, a pathologist and a radiologist discuss how the two disciplines can best work together to provide optimal healthcare, and we hear from the winners of the 2019 Educational Pathology Tweet Award. We also sit down with Rick Mitchell, Lawrence J. Henderson Professor of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, USA.

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Articles featured in this issue

Diagnostics Histology

Case of the Month

Can you diagnose this 53-year-old man who presented with scrotal pain and a 1.5 cm testicular mass?

Outside the Lab Profession

Preaching Beyond the Choir

| Michael Schubert

For patients to understand and appreciate our special profession, we have to do more to increase its exposure to the public

Diagnostics Clinical care

Delivering Better Care

| Michael Schubert

A blood test for placental growth factor can speed pre-eclampsia diagnosis by up to two days, reducing the likelihood of adverse events.

Diagnostics Genetics and epigenetics

The Right Dose for the Right Person

| Michael Schubert

New guidelines for CYPC29 genotyping ensure that the correct alleles are tested and patients are prescribed the correct doses of common drugs

Diagnostics Hematology

A SMArter Way to Diagnose Diabetes

| Michael Schubert

A new technique that spots damaged blood vessels by detecting proteins in the bloodstream could lead to earlier diagnosis and treatment of diabetes

Inside the Lab Digital and computational pathology

Long Live the (Digital) Revolution!

| Dariusz Borys

Pathology’s great strides forward in artificial intelligence and machine learning will bring us to the forefront of personalized medicine

Diagnostics Omics

Serving China’s Breast Cancer Community

| Franklin Libenson

Decentralized genomic testing in China will allow earlier breast cancer diagnosis and more personalized treatment decisions

Outside the Lab Laboratory management

The Limits of Automation

| Navaneeth Nair

Augmented intelligence should assist us in our decision-making, but cannot fully replace the human factor

Outside the Lab Profession

Cultivating Pathology’s Future

| E. Blair Holladay

Pathologists and laboratory medicine professionals do important work – and advocacy is the key to its continuation.

Outside the Lab Profession

The Spice of Life

| Luke Turner

Genomic research has a diversity problem that could restrict the future effectiveness of precision medicine for minority groups

Outside the Lab Clinical care

The Integration Equation

| W. Dean Wallace, Robert Suh

Pathologists and radiologists must work closely together to provide the best possible patient care

Inside the Lab Technology and innovation

HIER, Further, Faster

| Jason Ramos, Spontaneous Russell

Automated IHC staining has limited capacity for heat-induced epitope retrieval – but a move to hybrid power lifts that barrier.

Inside the Lab Laboratory management

The Evolution of a Lab Hero

| Jesse McCoy

Jesse McCoy explains what pathologists’ assistants do, where they come from, and how they serve as integral members of the laboratory medicine team

Outside the Lab Training and education

#MedEd Goes Social

| Michael Schubert

The winners of the 2019 Educational Pathology Tweet Award share their views on the future of education in pathology and laboratory medicine.

Routine Microscopy: Improving Productivity Through Better Ergonomics

| Contributed by Olympus Europa

In this article, James Geary, physiotherapist at the Royal Lancaster Infirmary, describes the issues encountered by professionals carrying out daily microscopy tasks.

Outside the Lab Profession

Balancing Benchtop and Bedside – and Ball Games

| Michael Schubert

We sit down with Rick Mitchell to discover why he chose pathology and how he manages to pursue so many activities outside of the lab.

Other issues of 2019