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In May’s issue of The Pathologist, we explore the concept of Clinical Lab 2.0, a grassroots movement whose ambition is to position the laboratory at the forefront of healthcare. Laboratorians and public health experts explain why, in the midst of a pandemic, the lab is more important than ever for safeguarding population health. Also in this issue, pulmonary pathologist Sanjay Mukhopadhyay explains the hidden dangers of vaping, David Dimond reveals why the creation and interoperability of metadata is essential for digital pathology, and we hear about the distinguished career of Christopher D.M. Fletcher. Finally, we sit down with Sarah Garner, Pathologists’ Assistant and Director of the Pathologists’ Assistant Program at Tulane University, New Orleans, Louisiana, USA.