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May 2017 Issue of The Pathologist

Our May 2017 issue discusses the growing workload of pathologists, a proposal for maximizing lab efficiency, and an approach for improving LC-MS. Also covered are visual biomarkers for melanoma, the importance of pathologist-patient interaction, genetic markers for anorexia, and pathology’s search for a “killer app”. Finally, we interview Susan Branford, Associate Professor at SA Pathology, Adelaide, Australia.

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Articles featured in this issue

Diagnostics Regulation and standards

DIY Pathology Panic

Can genetic home test kits ever be a good thing?

Subspecialties Clinical care

Case of the Month

What is the most likely diagnosis for this recurrent tumor from the leg of a 91-year-old man?

Subspecialties Genetics and epigenetics

Metabolic Mystery Revealed

| Michael Schubert

A genome-wide study shows that anorexia isn't purely psychiatric: metabolic factors also play a role

Inside the Lab Analytical science

A PCR Technique Out of Left Field

| Roisin McGuigan

Using left-handed DNA to better monitor and control PCR

Subspecialties Oncology

The Rise of ctDNA, Part One

| Roisin McGuigan

New ctDNA assays could make more metastatic melanoma cases detectable

Inside the Lab Oncology

The Rise of ctDNA, Part Two

| Michael Schubert

Circulating tumor DNA profiling can yield new insights into early-stage lung cancer evolution

Inside the Lab Oncology

Computers Catching Cancer

| Michael Schubert

A deep-learning network that detects invasive breast cancer may lighten the load for diagnosticians

Subspecialties Genetics and epigenetics

More Than a Gut Feeling

| Michael Schubert

A test to profile intestinal microbiota could help diagnose inflammatory bowel disease

Subspecialties Clinical care

Cracking a Cold Case

| Roisin McGuigan

A 30-year-old medical puzzle leads researchers to develop a new molecular therapy

Outside the Lab Profession

Foreseeing a Delectable Land

| David Booker

Open minds and eyes are the requirements for the future of pathology

Diagnostics Regulation and standards

Seeking the Killer App

| David Rimm

An examination of domain-specific companion diagnostic testing

Outside the Lab Quality assurance and quality control

Beyond Stone-Age Sample Prep

| Rodrigo Martinez-Duarte

Miniature detection technologies are evolving fast – but unevolved sample preparation is holding us back

Outside the Lab Training and education

All In a Day’s Work

| Raymond Maung

Just how much should pathologists be working - and what happens if we exceed our limits?

Outside the Lab Training and education

A Clinical Calculus

| Carol Cheung

Tools that quantify the (increasing) workloads of (increasingly) busy pathologists can help with staffing decisions

Outside the Lab Profession

Gearing Up for Change

| Gene Elliott

Can laboratories cope with the rising pressure to adopt new diagnostic technologies?

Inside the Lab Analytical science

What if Aesop’s Tortoise Were Smarter?

| Fred Regnier

Rethinking the chromatography component of routine LC-MS bioanalysis

Subspecialties Digital and computational pathology

Is Seeing Believing?

| Dan Gareau

Digital imaging software could unlock a new realm of visual biomarkers for detecting melanoma

Outside the Lab Profession

Pathology for the People

| Ulysses Balis

Could patient-facing pathologists close the information gap?

Subspecialties Profession

Sequencing, Stratifying, and Standardizing

| Michael Schubert

Susan Branford, Associate Professor, Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, Australia

Other issues of 2017