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April 2020 Issue of The Pathologist

April’s issue of The Pathologist sees the return of our gallery special feature for a fifth year running. We asked you, our readers, to send us your favorite artwork from the medical laboratory – and we’ve collated all the weird and wonderful submissions to create a unique and vibrant pathology art gallery! Also in this issue, Bobbi Pritt explains how to best use molecular assays in the diagnosis of infectious diseases, two high-profile innovators describe new diagnostic technologies, and Kamran Mirza investigates how others can learn from the lab’s unbiased approach to healthcare. We also sit down with Markku Miettinen, Senior Clinician and Head of the General Surgical Pathology Section, Laboratory of Pathology, National Cancer Institute/National Institutes of Health, Bethesda, Maryland, USA.

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Articles featured in this issue

Subspecialties Hematology

In Focus: Diffuse Large B-Cell Lymphoma

| Iffat Jamal

Diffuse large B-cell lymphoma, the most common non-Hodgkin’s lymphoma, rarely presents in the leukemic phase – but what happens when it does?

Subspecialties Hematology

Hematology: Challenges and Opportunities

| Michael Schubert

Some of the key challenges and shortfalls identified in a recent survey of the hematology laboratory workforce

Outside the Lab Profession

Business in Brief

| Luke Turner

Discover some of the latest business announcements from the world of laboratory medicine

Diagnostics Infectious disease

Behind the COVID Curve

| Luke Turner

Diagnostic testing for coronavirus suffered from a slow initial response in the US – but officials are ramping up efforts to get back on track

Subspecialties Infectious disease

What’s Up With Bats?

| Michael Schubert

Why are viruses that originate in bats so virulent when they infect human hosts?

Outside the Lab Infectious disease

Yes, We Gly-Can!

| Michael Schubert

Glycans used in the SARS-CoV-2 infectious process could offer faster, easier diagnosis

Outside the Lab Profession

The Kids’ Club

How X-WOW! is helping to inspire the next generation of African scientists by introducing them to the enthralling world of microscopy

Diagnostics Microscopy and imaging

Case of the Month

A 59-year-old man presented with left upper quadrant discomfort and was found to have hepatosplenomegaly – but what is your diagnosis?

Diagnostics Genetics and epigenetics

The African Imperative

| Aminu Yakubu

Genomics research is hampered by the fact that current reference genomes don’t take into account the vast diversity of human populations

Outside the Lab Training and education

A Model Career

| William Schreiber

If we want to encourage medical students to choose pathology, we have to serve as visible role models for the profession

Diagnostics Microscopy and imaging

The Future of Microscope Imaging

| Jürgen Reymann

Microscopy is an ever-evolving field – and its next step may be into fully integrated, digitized systems that offer a wealth of new information

Inside the Lab Digital and computational pathology

AI’s Evolving Role

| Gillian Beamer

Gillian Beamer gives her view on the future of AI in pathology, including how she uses algorithms to diagnose infection with tuberculosis

Outside the Lab Infectious disease

Laboratories in the Age of the Pandemic

| E. Blair Holladay

Laboratory medicine is key to fighting the pandemic, but we must work together to provide the best information and services to clinicians and patients

Outside the Lab Profession

Worth a Thousand Words

We celebrate some of the most beautiful hidden artwork from the medical laboratory – from stunning slides to abstract artistry and more...

Diagnostics Liquid biopsy

Test, Treat, Repeat

| Alexandra Pender, Natacha Entz-Werle

New ctDNA biomarkers could lead to more informed treatment decisions for patients with advanced non-small cell lung cancer and pediatric osteosarcoma

Outside the Lab Profession

It’s Time to Talk

| Jeffrey Myers, Lotte Mulder, Michele Mitchell

Pathologists play a key role in patient care – and that’s why patient-pathologist interactions are vital

Outside the Lab Profession

Microscopes, Ambulances, and Humanity

| Kamran Mirza

How the pathologist’s service to a patient is a rare example of an unbiased approach to healthcare – and life

Subspecialties Oncology

The GIST of It

| Michael Schubert

Markku Miettinen shares observations from an illustrious career in surgical pathology from both a research and a clinical perspective

Other issues of 2020