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April 2018 Issue of The Pathologist

The April issue of The Pathologist features a tour of Great Ormond Street Hospital, one of the most prominent pediatric hospitals in the world. We speak with people across various departments to find out how the hospital stays on top of the plethora of patient samples they take in. We also look into progeria biomarkers, infrared biopsy grading. This issue also dives into histopathology training in Sudan, the power of DNA methylation, and medical career path differences between Pakistan and the UK. And this month we sit down with Sarah Coupland, Professor of pathology at the University of Liverpool.

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Articles featured in this issue

Outside the Lab Profession

Sharing the Salt

Communication with colleagues and patients only leads to benefits

Outside the Lab Histology

Case of the Month

Can you diagnose the horse from these histopathology slides?

Subspecialties Genetics and epigenetics

Adding to the CNS Tumor Toolbox

| William Aryitey

DNA methylation and crowdsourcing may help classify CNS cancers

Diagnostics Genetics and epigenetics

A Protein Probe for Progeria

| William Aryitey

Delving into biomarkers for progeria may help track the disease’s progression

Subspecialties Oncology

Cost-effective Cancer Checks

| William Aryitey

Testing the whole population of women for breast/ovarian cancers mat be more cost-effective than current methods

Inside the Lab Oncology

Controlling CTC Capture

| William Aryitey

A nanotechnology-based assay could increase circulating tumor cell capture

Inside the Lab Biochemistry and molecular biology

Sensitive Joints

| William Aryitey

A nanopore sensor can boost the sensitivity of an osteoarthritis biomarker

Subspecialties Histology

H&E’s IR Upgrade

| William Aryitey

Boosting the accuracy of biopsy grading with Digistain

Outside the Lab Histology

New Horizons in Histopathology Training

| Azza Zulfu

Training and education in Sudan is greatly improving, but there are still a few hurdles to overcome

Outside the Lab Analytical science

In Service to Our Smallest Patients

| Simon Heales

We take a tour through one of the world’s most foremost pediatric institutes, the Great Ormond Street Hospital

Subspecialties Screening and monitoring

Enzymology: A Whistle-Stop Tour of GOSH Pathology

| Derek Burke

How do the labs at GOSH use enzyme assays to help their infant patients?

Diagnostics Microbiology and immunology

Microbiology: A Whistle-Stop Tour of GOSH Pathology

| Elaine Cloutman-Green

We explore GOSH’s interesting approach to microbiology

Subspecialties Histology

Histopathology: A Whistle-Stop Tour of GOSH Pathology

| Toby Hunt

What separates GOSH’s pediatric histopathology department from other institutions?

Outside the Lab Laboratory management

Flow Cytometry: A Whistle-Stop Tour of GOSH Pathology

| Sarah Inglott

Collaborations and translational research mean GOSH’s flow cytometry lab serves patients in the best way possible

Outside the Lab Biochemistry and molecular biology

Rapid Response: A Whistle-Stop Tour of GOSH Pathology

| Simon Heales

GOSH’s high-throughput 24-hour lab offers quick results without compromising quality

Diagnostics Oncology

Tackling the Testing Challenge in Lung Cancer

| Neil Lindeman

Can revised guidelines help improve treatment for lung cancer patients?

Inside the Lab Genetics and epigenetics

The Diagnostic Power of DNA Methylation

| Bekim Sadikovic

Machine learning and DNA methylation could open up a new realm of diagnostic possibility

Outside the Lab Training and education

Dissecting Brain from Brawn

| Austin McHenry and Kamran Mirza

Choosing a medical specialty isn’t easy, but students often shy away from pathology. Why is that?

Outside the Lab Profession

A Tale of Two Countries

| Ayesha Azam

Ayesha Azam compares the medical career paths in Pakistan and the UK

Subspecialties Profession

A Vision for Pathology

| Michael Schubert

Sitting Down With Sarah Coupland, Professor of Pathology at the University of Liverpool

Other issues of 2018