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February 2020 Issue of The Pathologist

In our first issue of 2020, we scrutinize the way that research productivity is currently measured in pathology – and ask whether there is a better way. Michael Bonert, Gaurav Vasisth, Christopher Naugler, and Asghar Naqvi explore an alternative metric by which to evaluate contributions to the academic literature that uses freely available data from USCAP’s Annual Meeting abstracts. In addition, learn some tips and tricks for an effective clinical pathology consultation, hear from two high-profile innovators as they discuss their diagnostic inventions, and read about a unique collaboration between pathologist and rockstar. We also sit down with Nicola Parry, Independent Veterinary Pathology Consultant at Midwest Veterinary Pathology, Lafayette, Indiana, USA.

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Articles featured in this issue

Outside the Lab Profession

Five Years and Counting

| Michael Schubert

How has pathology changed over the last five years – and what doesn’t seem to have changed at all?

Subspecialties Neurology

Predicting Prognosis in Glioblastoma

| Luke Turner

A link between cfDNA concentration and progression-free survival in glioblastoma patients supports the use of liquid biopsy when predicting prognosis

Subspecialties Microbiology and immunology

Non-Tuberculous Mycobacteria

| Michael Schubert

Reports on NTM lung disease – the risks, the symptoms, and the patient data

Outside the Lab Point of care testing

A Question of Quality

| Luke Turner

This year’s International Pathology Day was all about point-of-care testing – so how do the experts think quality can be delivered across the board?

Subspecialties Microbiology and immunology

TB Triage

| Luke Turner

A blood-based triage test for TB could provide a cheap and reliable point-of-care diagnostic for people in low-resource areas

Diagnostics Biochemistry and molecular biology

Molecular Diagnostics on the Rise

| Michael Schubert

Accurate, safe, and dependable diagnostic tools are crucial – and this is where molecular diagnostics has the opportunity to shine

Diagnostics Biochemistry and molecular biology

Cancer Trap

| Luke Turner

New synthetic scaffolds that sit under the skin and attract cancer cells could provide the earliest indication of metastasis

Inside the Lab Digital and computational pathology

Mutation Detective

| Luke Turner

A new algorithm finds that a quality control process to remove nonsense mutations in our immune system could be having an undesired effect

Outside the Lab Profession

Quote of the Month

| Christopher D.M. Fletcher

What do you do when you come across a case that you can't solve? There isn't always an answer for everything, according to these words of wisdom

Diagnostics Histology

Case of the Month

Case of the Month is back for 2020! Can you diagnose this 71-year-old female who presented with an incidental osseous nasal septum mass?

Diagnostics Companion diagnostics

Which Assay for Atezolizumab?

| Emina Torlakovic, Allen M. Gown

Emina Torlakovic and Allen Gown share their disagreements with David Rimm’s comments about an FDA-approved PD-L1 assay for atezolizumab

Inside the Lab Laboratory management

Come Together

| Dariusz Borys

Interdisciplinary collaboration can build strong pathology departments and offer patients faster, more accurate diagnosis

Outside the Lab Profession

The Laboratory: Critical to Sports

| E. Blair Holladay

Pathologists and laboratory medicine professionals are a crucial part of the Olympic Games and other elite sporting events

Outside the Lab Profession

The Best Metric of Success

| Michael Bonert, Gaurav Vasisth, Christopher Naugler, Asghar Naqvi

A next-generation measure of academic productivity using USCAP’s Annual Meeting abstracts could provide a fairer metric for researchers

Inside the Lab Laboratory management

Trust Is Earned

| Gene R. Shaw

How can clinical pathologists and clinical PhDs effectively collaborate with colleagues who interact directly with patients to improve overall care?

Inside the Lab Technology and innovation

Inspiring Inventions

| Michael Schubert

The inventors of new diagnostic technologies discuss their innovations and how they can move laboratory medicine forward

Outside the Lab Profession

Come on Pathology, Light My Fire

| Luke Turner

After Michael Misialek contacted Robby Krieger of legendary rock band The Doors, they teamed up to raise crucial funds – and awareness – for pathology

Outside the Lab Technology and innovation

Midas Touch or Fool’s Gold?

| Richard Huang, Veronica Klepeis

The FDA has introduced new regulatory frameworks to ease digital medical devices’ transition to market – so why aren’t pathology companies using them?

Outside the Lab Profession

The Veterinary Pathologist

| Michael Schubert

Nicola Parry describes her career in veterinary pathology, including her views on the future and her experiences in giraffe autopsy!

Other issues of 2020