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January 2018 Issue of The Pathologist

Our first issue in 2018 covers the promise of computational pathology in the first of a two-part feature – three gurus explain how it can help enhance pathologists’ work. We also look into chimerism overcoming transplant rejection, the critical importance of inter-departmental teamwork, and how the WHO’s Blue Books evolve to keep up with the changing classifications of cancer. Plus, we sit down with Richard J. Ablin, the man behind the discovery of prostate specific antigen (PSA).

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Articles featured in this issue

Outside the Lab Technology and innovation

Turn On, Tune In…

| Michael Schubert

Is social media the best way to talk and share your slides with fellow pathologists?

Subspecialties Clinical care

Case of the Month

Six-week-old female presented with a history of volvulus on the second day of life

Subspecialties Microbiology and immunology

A Closer Look at Chimerism

| Michael Schubert

Research about the underlying pathways of chimeric transplant tolerance may aid immunosuppression

Outside the Lab Oncology

A Drop of the Good Stuff

| Michael Schubert

Discontinuing leukemia treatment without cancer recurrence may be a little safer thanks to ddPCR

Diagnostics Screening and monitoring

A Breath of Fresh Air

| Michael Schubert

Particles from your breath could offer diagnostic value for small airway diseases

Subspecialties Oncology

Spot the Fusion

| Michael Schubert

Predicting pancreatic lesion malignancy risk is only an assay away with a PCR-based technique

Outside the Lab Regulation and standards

Innovation Versus Exnovation

| Roisin McGuigan

Could heading in the opposite direction of innovation be a viable way to progress medicine?

Inside the Lab Genetics and epigenetics

Elementary, My Dear Watson

| Michael Schubert

IBM's Watson takes a dive into the field of genomics to look for actionable cancer mutations

Subspecialties Oncology

Can’t Stop the Signal

| Michael Schubert

An investigation into PARP1 has given some insight into its link with cancer treatment-resistance

Outside the Lab Profession

Collaboration Through Communication

| Michael Prystowsky

When healthcare teams and pathologists effectively communicate, everyone wins

Inside the Lab Digital and computational pathology

The Promise Of Computational Pathology: Part 1

| Jeroen van Laak, Nasir Rajpoot, and Dirk Vossen

Three gurus weigh in on what computational pathology holds for pathologists and the future of the field

Subspecialties Oncology

A Stromal Solution

| Marloes Smit and Wilma Mesker

Could the tumor-stroma ratio (TSR) yield more accurate reuslts than the tumor-node-metastasis (TMN) system?

Diagnostics Oncology

Making a Difference with Microdeletions

| Rosemary Sutton and Toby Trahair

A higher survival rate and more accurate prognosis may come from testing tiny genetic alterations

Diagnostics Point of care testing

Acid Test

| Michael Mason

Testing DNA/RNA from living organisms is now as easy as using a dipstick

Diagnostics Genetics and epigenetics

An Answer Out of Time

| Alan M. Lambowitz, Jennifer Stamos, Alfred M. Lantzsch, and Yidan Qin

Ancestral functions of the TGIRT enzyme could help the hunt for better liquid biopsy for RNA

Outside the Lab Oncology

Onward and Upward for the Blue Books

| Ian Cree

Read the tale behind the tumor classification reference books put together by the WHO's IARC

Subspecialties Profession

Traded for a Microscope!

| Michael Schubert

Sitting Down With… Richard J. Ablin, Professor of Pathology, University of Arizona College of Medicine

Other issues of 2018