When the Current Serves
Sitting Down With… Anant Madabhushi, F. Alex Nason Professor II of Biomedical Engineering and Director of the Center for Computational Imaging and Personalized Diagnostics at Case Western Reserve University, Cleveland, USA
Luke Turner | | Hot Topic
Why did you pursue digital and computational pathology?
My initial plan was to study medicine, but my application was unsuccessful. Biomedical science seemed like the next best thing and it was a subject I could get excited about, so I began my degree in biomedical engineering in Bombay, India. During my studies, I was exposed to medical imaging and realized that the integration of computer science and imaging was a sweet spot for me. I began to develop pattern recognition algorithms, not to find cancer, but to find people in videos and to recognize certain movements.
During my PhD, I really started to zero in on the computational analysis of medical images, starting with radiography. I was fortunate enough to meet two pathologists: Mike Feldman and John Tomaszewski. One day, Mike said to me, “Imagine if you could digitize this little slide and start to interrogate it computationally; think about the opportunities.” I picked it up and replied, “This little thing? That should be trivial!” I didn’t realize that one small slide would produce gigabytes of data! That was just the beginning – shortly thereafter, we published the first paper on digital pathology.
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