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Inside the Lab Digital and computational pathology, Histology, Microbiology and immunology, Microbiology and immunology, Microscopy and imaging, Microscopy and imaging, Cytology, Oncology, Neurology, Technology and innovation, Laboratory management

Through the Looking Glass Continued

Renal Biopsies

Top to bottom: renal biopsy with Martius scarlet blue (MSB) staining for fibrin, collagen and muscle tissue; renal biopsy with Jones’ stain for basement membrane; renal tissue control with MSB staining.

José Bernardino

Arterial Supply

The image, in pen and ink on paper, shows the arterial supply of blood to the hand.

Credit: David R S Evans, Cardiff University, Affiliate Member of the Artists’ Association

Fire-Breathing Dragon

This image of a breast fibroadenoma shows branching cohesive ductal epithelial cell groups with associated intrinsic smaller and somewhat spindled myoepithelial cells, scattered stripped bipolar nuclei, a magenta strand of hypocellular fibrous stroma – and a fearsome beast that belies the benign nature of the condition.

Charles Sturgis, Cleveland Clinic

“The coroner wants an autopsy to confirm the cause of death!"

Merlyn Harvey

Dendritic Cell

Serial block-face scanning electron micrograph with 3D reconstruction of a dendritic cell shown in its ultrastructure.

Peter Munro and Hannah Armer, UCL Institute of Ophthalmology; ZEISS Microscopy

Step By Step

Walking through a breast tissue fine needle aspiration. The lighter-colored cells are ductal cells, whereas darker ones are myoepithelial cells from a benign lesion.

Lara Pijuan

Cancer Crater

Keratoacanthoma in the abdominal skin of a male Caucasian patient. This image was captured on a MetaSystem Metafer VSlide scanner.

Lukas Lacina, Declan P Lunny, Ildiko Szeverenyi, Sarah Zulkifli, Graham D Wright, Institute of Medical Biology, A*STAR, Singapore

Taking Wings

There are those who label behind-the- scenes medicine “boring” – but show them this rainbow in a tissue stain and they’ll see how pathology can reveal hidden beauty.

Priti Lal

Driving a Car Up the Hill

You can find art and humor in your day- to-day work, proving that pathology can be both funny and functional.

Lenka Bartonova

The Secrets of Digital Imaging

From top: An open whole slide scanner, revealing what’s inside the box; using a digital pathology workstation to check case management and workflow; the digital imaging research laboratory at UPMC; using a virtual reality headset to screen and interpret digital Pap tests; testing smartphones for telepathology using real-time viewing.

Liron Pantanowitz on behalf of the Division of Pathology Informatics at the University of Pittsburgh Medical Center (UPMC)

The Reconstructed Gut

A 3D reconstruction of a right hemicolectomy specimen composed of about 100,000 texture mapped polygons. This image is a screenshot of the flight plan for a flyover animation; the orange pyramid indicates a virtual camera and the black line the path it will follow. See the video at “My hope is that such videos will spur interest in anatomy and anatomic pathology in young adults using a powerful medium that they’re familiar with.”

Shane Battye


This wax écorché anatomical figure was based upon the Paralympian athlete Richard Whitehead and shown as part of an exhibition entitled “Anatomy of an Athlete” at the Huntarian Museum in London.

Richard Neave and Denise Smith

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About the Author
Michael Schubert

While obtaining degrees in biology from the University of Alberta and biochemistry from Penn State College of Medicine, I worked as a freelance science and medical writer. I was able to hone my skills in research, presentation and scientific writing by assembling grants and journal articles, speaking at international conferences, and consulting on topics ranging from medical education to comic book science. As much as I’ve enjoyed designing new bacteria and plausible superheroes, though, I’m more pleased than ever to be at Texere, using my writing and editing skills to create great content for a professional audience.

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