Conexiant
Login
  • The Analytical Scientist
  • The Cannabis Scientist
  • The Medicine Maker
  • The Ophthalmologist
  • The Pathologist
  • The Traditional Scientist
The Pathologist
  • Explore Pathology

    Explore

    • Latest
    • Insights
    • Case Studies
    • Opinion & Personal Narratives
    • Research & Innovations
    • Product Profiles

    Featured Topics

    • Molecular Pathology
    • Infectious Disease
    • Digital Pathology

    Issues

    • Latest Issue
    • Archive
  • Subspecialties
    • Oncology
    • Histology
    • Cytology
    • Hematology
    • Endocrinology
    • Neurology
    • Microbiology & Immunology
    • Forensics
    • Pathologists' Assistants
  • Training & Education

    Career Development

    • Professional Development
    • Career Pathways
    • Workforce Trends

    Educational Resources

    • Guidelines & Recommendations
    • App Notes

    Events

    • Webinars
    • Live Events
  • Events
    • Live Events
    • Webinars
  • Profiles & Community

    People & Profiles

    • Power List
    • Voices in the Community
    • Authors & Contributors
  • Multimedia
    • Video
    • Podcasts
    • Pathology Captures
Subscribe
Subscribe

False

The Pathologist / Issues / 2021 / Oct / That’s the SPIRIT
Guidelines and Recommendations Quality assurance and quality control Regulation and standards

That’s the SPIRIT

New guidelines aim to address variability in pathology evaluation in clinical trials

By Liv Gaskill 10/14/2021 Quick Read (pre 2022) 1 min read

Share

To address the variability in the way cellular and molecular pathology are reported in clinical trial protocols, an international group of cancer researchers has published new guidelines – named “SPIRIT-Path.” The guidance recommends that “protocols should document the individuals, processes, and standards for all cellular and molecular pathology components of the trial, including all stages of the specimen pathway and any digital pathology methods, with specific consideration of the value of trial data and biological tissues for additional translational studies (1).”

Tim Kendall, Co-Chair of the National Cancer Research Institute’s SPIRIT-Path working group, said, “The SPIRIT-Path extension will allow investigators to comprehensively address the cellular and molecular pathology aspects of trial protocols, ensuring adequate skills and resources are available at trial commencement, and fully leverage the value of biospecimens for translational research (2).”

Newsletters

Receive the latest pathologist news, personalities, education, and career development – weekly to your inbox.

Newsletter Signup Image

References

  1. TJ Kendall et al., Lancet Oncol, 22, e435 (2021). PMID: 34592193.
  2. R Laurence (2021). Available at: https://bit.ly/2WF0jrk.

About the Author(s)

Liv Gaskill

During my undergraduate degree in psychology and Master’s in neuroimaging for clinical and cognitive neuroscience, I realized the tasks my classmates found tedious – writing essays, editing, proofreading – were the ones that gave me the greatest satisfaction. I quickly gathered that rambling on about science in the bar wasn’t exactly riveting for my non-scientist friends, so my thoughts turned to a career in science writing. At Texere, I get to craft science into stories, interact with international experts, and engage with readers who love science just as much as I do.

More Articles by Liv Gaskill

Explore More in Pathology

Dive deeper into the world of pathology. Explore the latest articles, case studies, expert insights, and groundbreaking research.

False

Advertisement

Recommended

False

Related Content

Microbiology and climate change: Building a sustainable future together
Guidelines and Recommendations
Microbiology and climate change: Building a sustainable future together

January 27, 2022

1 min read

Serum Rhubarb Please… Stat!
Guidelines and Recommendations
Serum Rhubarb Please… Stat!

February 25, 2022

10 min read

We must weigh the benefits and risks of every test we perform – our patients’ lives hang in the balance

The Need for Nuance in a Polarizing Pandemic
Guidelines and Recommendations
The Need for Nuance in a Polarizing Pandemic

July 27, 2022

4 min read

From politics to pandemic fatigue, the long road from 2020 came with a series of hurdles that stopped an effective response in its tracks

IVDR Compliance: A Marathon, Not a Sprint
Guidelines and Recommendations
IVDR Compliance: A Marathon, Not a Sprint

September 13, 2022

3 min read

Reaching the IVDR compliance finishing line requires significant time and resources – but it’s an investment that will pay off in spades

False

The Pathologist
Subscribe

About

  • About Us
  • Work at Conexiant Europe
  • Terms and Conditions
  • Privacy Policy
  • Advertise With Us
  • Contact Us

Copyright © 2025 Texere Publishing Limited (trading as Conexiant), with registered number 08113419 whose registered office is at Booths No. 1, Booths Park, Chelford Road, Knutsford, England, WA16 8GS.