Cookies

Like most websites The Pathologist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Inside the Lab Microscopy and imaging, Biochemistry and molecular biology, Analytical science, Technology and innovation

Image of the Month: X-Ray Vision

Using an X-ray-sensitive lanthanide-binding tag (LBT), scientists have demonstrated a new technique for imaging proteins in 3D at nanoscale resolution. By combining LBT with X-ray fluorescence, the method enables researchers to precisely locate proteins within individual cells, reaching the resolution of even the smallest subcellular organelles. In the above image, the technique reveals the concentrations of erbium (yellow) and zinc (red) in an E. coli cell expressing an LBT tag.

Credit: Brookhaven National Laboratory

Subscribe to The Pathologist Newsletters

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].

  1. TW Victor et al., J Am Chem Soc, 142, 2145 (2020). PMID: 31923358.

Register to The Pathologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine

Register