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Inside the Lab Microbiology and immunology, Screening and monitoring, Clinical care, Laboratory management

Exosome Exploration

“There is a critical need for time-sensitive, noninvasive biomarkers to monitor transplant organ rejection or injury,” says Prashanth Vallabhajosyula, assistant professor of surgery at the Hospital of the University of Pennsylvania. “In transplant patients, complications associated with transplant organ rejection/injury, and with the required immunosuppressive drugs, are the major causes of morbidity and mortality. Therefore, any biomarker platform that can accurately enable noninvasive monitoring of the transplanted organ would have a direct translational impact.” To that end, Vallabhajosyula and a team of researchers (also from the University of Pennsylvania) showed that blood-based transplant exosomes can be a noninvasive alternative to needle biopsy in islet and renal transplants (1).

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About the Author

William Aryitey

My fascination with science, gaming, and writing led to my studying biology at university, while simultaneously working as an online games journalist. After university, I travelled across Europe, working on a novel and developing a game, before finding my way to Texere. As Associate Editor, I’m evolving my loves of science and writing, while continuing to pursue my passion for gaming and creative writing in a personal capacity.

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