Cookies

Like most websites The Pathologist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Inside the Lab Oncology, Bioinformatics, Genetics and epigenetics, Clinical care, Technology and innovation, Omics

Big Data, Hidden Knowledge

Big Data, Hidden Knowledge

Novel mathematical tools show promise in predicting ovarian cancer patient survival and sensitivity to platinum-based chemotherapy.

By Fedra Pavlou

At a Glance

  • Most ovarian cancer cases are diagnosed in advanced stages, and no diagnostic exists that distinguishes tumors that are resistant to traditional chemotherapy from those that aren’t
  • A team based at the University of Utah have developed a mathematical tool that analyzes DNA profiles from the Cancer Genome Atlas to discover patterns of DNA anomalies
  • Using this approach, they have been able to predict a woman’s outcome significantly better than can be done with the tumor’s stage; it is also the first known indicator of how well a woman will respond to platinum therapy
  • These DNA patterns could be the basis of a personalized prognostic and diagnostic laboratory test. The researchers continue to assess the patterns in ovarian cancer and plan to expand their mathematical modeling to other tumor types

Read the full article now

Log in or register to read this article in full and gain access to The Pathologist’s entire content archive. It’s FREE and always will be!

Login

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine
Register

Or Login via Social Media

By clicking on any of the above social media links, you are agreeing to our Privacy Notice.

About the Author

Fedra Pavlou

After graduating with a pharmacology degree, I began my career in scientific publishing and communications. Now with more than 16 years of experience in this field, my career has seen me heading up editorial and writing teams at Datamonitor, Advanstar and KnowledgePoint360 group. My past experiences have taught me something very important – that you have to enjoy working with, and have respect for your colleagues. It’s this that drew me to Texere where I now work with old colleagues and new. Though we are a hugely diverse team, we share several things in common – a real desire to work hard to succeed, to be the best at what we do, never to settle for second best, and to have fun while we do it. I am now honored to serve as Editor of The Pathologist and Editorial Director of Texere Publishing.

Register to The Pathologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine

Register