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Inside the Lab Companion diagnostics, Clinical care, Precision medicine

Benchmarking Companion Diagnostics

New medical interventions often get a lot of media attention – but less is given to companion diagnostics, diagnostic tests and devices that provide essential information for the use of a corresponding intervention. But companion diagnostics are vital to the safety and efficacy of those interventions; they help physicians decide which patients should receive a particular therapy,  which patients need to be monitored more closely, and which patients are responding appropriately to treatment.

But what do those “on the ground,” developing and using companion diagnostics, think? What are your peers reading and researching? To find out, we decided to benchmark all of the PubMed-listed literature on the topic. We asked:

  • What are the major topics the field?
  • Which journals have the greatest impact?
  • How is the knowledge available online?
  • What types of articles are being published?
  • Who are the most prolific authors?

Article Categorization by Number of Publications

Fee or Free?

Top 20 Important Words


Here are the top 20 important words found in the literature. Important words have more frequent occurrences in the result subset than in MEDLINE as a whole; therefore they distinguish the result subset from the rest of MEDLINE.

Top 20 Journals by Impact Factor

Top 20 Journals by Number of Publications

20 Most Prolific Authors

Top 20 Journals by Eigenfactor

Publications by Language

Countries by Number of Publications

PubMed was searched for “companion diagnostic.” The data were analyzed in Microsoft Excel 2013.

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