Subscribe to Newsletter
Inside the Lab Neurology, Technology and innovation

Benchmarking Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS), also known around the world as Lou Gehrig’s disease, Charcot disease or motor neurone disease, is a neurodegenerative condition that causes motor neuron death in the brain and spinal cord. There is no cure, and the origin of disease is unclear in the vast majority of cases. As a field in desperate need of better therapies, ALS researchers received a windfall last summer, when the “ice bucket challenge” significantly raised their profile, and their funding. Although it remains to be seen if this funding boost can be sustained, one thing is certain – researchers have been working to better understand ALS before it found fame, and their work will continue even if the condition returns to its previous semi-obscurity.

To provide insight into past research priorities, and predictions for the future of the field, a series of metrics were applied to the last five years of the published literature. We asked:

  • What are the major topics for the field?
  • Which publications have the  greatest impact?
  • How is the knowledge available online?
  • Who are the most prolific authors?

Top 20 Authors by Number of Publications

Top 20 Important Words

Fee or Free?

Publications per Year

Top 20 Journals by Impact Factor

Top 20 Journals by No. of Publications


Categorization of Articles

Publications by Country

PubMed was searched for “amyotrophic lateral sclerosis” and “diagnosis” (for a diagnostic focus) with results limited to the last five years, in humans (for a clinical focus). The data were analyzed in Microsoft Excel 2013.

Receive content, products, events as well as relevant industry updates from The Pathologist and its sponsors.
Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

About the Author
Roisin McGuigan

I have an extensive academic background in the life sciences, having studied forensic biology and human medical genetics in my time at Strathclyde and Glasgow Universities. My research, data presentation and bioinformatics skills plus my ‘wet lab’ experience have been a superb grounding for my role as an Associate Editor at Texere Publishing. The job allows me to utilize my hard-learned academic skills and experience in my current position within an exciting and contemporary publishing company.

Related Application Notes
Biomarker Optimization on LabSat® Research

| Contributed by Lunaphore Technologies

Fast and automated TSA-based multiplexed immunofluorescence on LabSat® Research

| Contributed by Lunaphore Technologies

Specific Detection of RNA Expression and Distribution in Brain Using RNAscope® Technology

| Contributed by ACD

Most Popular
Register to The Pathologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:
  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine