3D Tissue Staining Visualizes Whole Organs
New staining technique opens the door to 3D histopathology
Luke Turner | | Quick Read
3D tissue imaging holds great promise – but although tissue clearing can produce stunning images, it has little scientific value on its own. To study specific tissue and cell types, a versatile staining and labeling method that works across a range of staining agents and antibodies is needed. A team from Japan have now developed exactly that, using their technique, CUBIC-HistoVIsion, to stain and image not just tissues, but even an entire mouse brain (1). Etsuo Susaki from the RIKEN Center for Biosystems Dynamics Research explains more.
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